This document was completed by Martina Cartwright, PhD Senior Director, Medical Affairs and Dr. Alessndro Mazzetti, Chief Medical Officer, Cassiopea. The product being discussed, clascoterone cream 1% is NOT FDA approved and is for informational purposes only.
FightAcne.com: What is the background for this study?
Response: Androgens play a significant role in the development of acne in both males and females. Oral medications that reduce androgens are used to treat acne in females, but due to side effects, are unsuitable for males. Clascoterone cream 1% is a novel, topical androgen receptor inhibitor under FDA review as possibly a new first in class treatment for acne in both males and females. These pivotal phase 3 studies demonstrated favorable efficacy and safety with low adverse event rates.