This article discusses use of topical dapsone used once daily for the treatment of acne, including adverse effects.
J Drugs Dermatol. 2017 Jun 1;16(6):591-598.
Treatment Response With Once-Daily Topical Dapsone Gel, 7.5% for Acne Vulgaris: Subgroup Analysis of Pooled Data from Two Randomized, Double-Blind Stu.
Draelos ZD, Rodriguez DA, Kempers SE, Bruce S, Peredo MI, Downie J, Chang-Lin JE, Berk DR, Ruan S, Kaoukhov A.