Acne Scars: Trial Tests Microneedling With Insulin and Vitamin C

FightAcne.com Interview with:
Mohamed L. Elsaie, MD
Senator at the Egyptian Senate
Professor of Dermatology, NRC, Egypt
Fellow of the University of Miami; USA

Prof. Elsaie

FightAcne.com:  What is the background for this study? 

Response: Post acne scars following sebaceous injury and abnormal wound healing during the course of acne is a prevalent and challenging to treat condition To evaluate microneedling by dermapen with topical vitamin C versus microneedling with topical insulin in treating atrophic post-acne scars.

A split-face comparative study included 30 subjects with atrophic post-acne scars. Human insulin was topically applied to the left side of the face and on the right side, vitamin C serum was applied.

Benefits and Side Effects of Microneedling to Fight Acne

FightAcne.com Interview with:
Miesha Merati, DO, FAAD
The Parker Skin and Aesthetic Clinic
Beachwood, Ohio

FightAcne.com: Would you briefly explain the microneedling procedure and what it is used for?

Response: Microneedling has gained popularity over the recent years due to its accessibility, relative ease of use, and impressive results for a variety of skin concerns including scar remodeling, pigmentary disorders, alopecia, acne, rejuvenation and rhytide reduction. It is a minimally invasive procedure that uses a device with needles ranging from 0.5 to 3mm in length that puncture the epidermis, and sometimes the dermis in a controlled fashion. Penetration of the skin allows for the release of growth factors, collagen, elastin, and dermal drug delivery. Microneedling exists in many forms, including the roller device, dermastamp, automated pen, and fractional radiofrequency. 

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What Is Acne Keloidalis?



A keloid is a type of scar, that continues to grow and often itch, well after the underlying wound has healed.

Acne keloidalis is a type of scarring reaction most often seen on the nape of the neck or scalp.  Acne keloidalis may develop after a ‘close shave’ where the hairs have a chance to ingrow and cause inflammation and then scar.

Here’s a good case report:

Acne keloidalis nuchae: clinical and dermoscopic features

Chourouk ChoukNoureddine LitaiemMariem JonesFaten Zeglaoui
BMJ Case Reports 2017:published online 23 September 2017doi:10.1136/bcr-2017-222222

Note: Content is Not intended as medical advice. Please consult your health care provider regarding your specific medical condition and questions.

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Journal Offers Review and Practical Guide to Microneedling



Microneedling is a relatively new procedure designed to improve scars and other skin conditions with a minimum of down time.

Here is a link to a recent review of Microneedling:

Microneedling: A Review and Practical Guide.

Alster TS1, Graham PM.



Why Treat Acne?



The American Academy of Dermatology discusses the scarring of the skin and self esteem that are triggered by untreated acne.

https://www.aad.org/public/diseases/acne-and-rosacea/acne



A Review of Microneedling for Scars and Wrinkles



This is a review of the literature of microneedling for improvement of scars from a variety of causes including acne. Microneedling is also known as Collagen induction therapy or (CIT) .

http://www.sciencedirect.com/science/article/pii/S1748681517302504



How To Measure Acne Scarring?



This new study  presents the development and assessment of a tool aiming to assess the risk of atrophic acne scars.

J Eur Acad Dermatol Venereol. 2017 May 12. doi: 10.1111/jdv.14325. [Epub ahead of print]

Development of an atrophic acne scar risk assessment tool.

Tan J1, Thiboutot D2, Gollnick H3, Kang S4, Layton A5, Leyden JJ6, Torres V7, Guillemot J8,9, Dréno B1